The mitochondrial DNA control region shows genetically correlated levels of heteroplasmy in leukocytes of centenarians and their offspring

BACKGROUND: Studies on heteroplasmy occurring in the mitochondrial DNA (mtDNA) control region (CR) in leukocytes of centenarians and younger subjects have shown that the C150T somatic transition is over-represented in centenarians. However, whether the occurrence/accumulation of heteroplasmy is a ph...

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Detalhes bibliográficos
Main Authors: Rose, Giuseppina, Passarino, Giuseppe, Scornaienchi, Vittorio, Romeo, Giuseppe, Dato, Serena, Bellizzi, Dina, Mari, Vincenzo, Feraco, Emidio, Maletta, Raffaele, Bruni, Amalia, Franceschi, Claudio, De Benedictis, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014781/
https://ncbi.nlm.nih.gov/pubmed/17727699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-293
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