Somatic Point Mutations in mtDNA Control Region Are Influenced by Genetic Background and Associated with Healthy Aging: A GEHA Study

Tissue specific somatic mutations occurring in the mtDNA control region have been proposed to provide a survival advantage. Data on twins and on relatives of long-lived subjects suggested that the occurrence/accumulation of these mutations may be genetically influenced. To further investigate contro...

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Detalhes bibliográficos
Main Authors: Rose, Giuseppina, Romeo, Giuseppe, Dato, Serena, Crocco, Paolina, Bruni, Amalia C., Hervonen, Antti, Majamaa, Kari, Sevini, Federica, Franceschi, Claudio, Passarino, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954809/
https://ncbi.nlm.nih.gov/pubmed/20976236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013395
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