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Blood–brain distribution of morphine-6-glucuronide in sheep

BACKGROUND AND PURPOSE: At present there are few data regarding the rate and extent of brain–blood partitioning of the opioid active metabolite of morphine, morphine-6-glucuronide (M6G). In this study the cerebral kinetics of M6G were determined, after a short-term intravenous infusion, in chronical...

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Autors principals: Villesen, H H, Foster, D J R, Upton, R N, Christrup, L L, Somogyi, A A, Martinez, A, Grant, C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014650/
https://ncbi.nlm.nih.gov/pubmed/17016501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706916
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