Multiple dose study of interactions between artesunate and artemisinin in healthy volunteers

AIMS: To investigate whether coadministration of the antimalarials artesunate and artemisinin alters the clearance of either drug. METHODS: Ten healthy Vietnamese males (Group AS) were randomized to receive a single dose of 100 mg oral artesunate (pro-drug of dihydroartemisinin) on day −5 and then o...

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Detalhes bibliográficos
Main Authors: Zhang, Shu-Qiu, Hai, Trinh Ngoc, Ilett, Kenneth F, Huong, Dinh Xuan, Davis, Timothy M E, Ashton, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014589/
https://ncbi.nlm.nih.gov/pubmed/11678781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01461.x
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