Assessment of the Effect of Mefloquine on Artesunate Pharmacokinetics in Healthy Male Volunteers

The effect of mefloquine on artesunate pharmacokinetics was assessed in 20 volunteers given artesunate for 3 days, followed ≥21 days later by combination therapy for 3 days. The areas under the concentration-time curve from 0 h to infinity for dihydroartemisinin, the active metabolite of artesunate,...

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Detalhes bibliográficos
Main Authors: Davis, Timothy M. E., England, Michelle, Dunlop, Anne-Marie, Page-Sharp, Madhu, Cambon, Nathalie, Keller, Thomas G., Heidecker, János L., Ilett, Kenneth F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1803145/
https://ncbi.nlm.nih.gov/pubmed/17178798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01253-06
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