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Evidence of impaired cisapride metabolism in neonates

AIMS: Cisapride has been shown to cause QTc prolongation in neonates in the absence of any of the known risk factors ascribed to children or adults (excessive dosage, drug–drug interactions). Our hypothesis was that the early neonatal liver may show defective elimination of cisapride resulting in it...

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Detalhes bibliográficos
Main Authors: Tréluyer, Jean-Marc, Rey, E, Sonnier, M, Pons, G, Cresteil, T
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014576/
https://ncbi.nlm.nih.gov/pubmed/11678785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01470.x
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