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Carbamazepine is not a substrate for P-glycoprotein
AIMS: To determine whether the anticonvulsant carbamazepine (CBZ), a known CYP3A4 substrate, is also a substrate for the multidrug efflux transporter P-glycoprotein (Pgp). METHODS: The role of Pgp in the transport of CBZ was assessed in three systems: (a) in mdr1a/1b(−/−) and wild-type mice after ad...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Science Inc
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014449/ https://ncbi.nlm.nih.gov/pubmed/11318771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2001.01359.x |
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