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Validation of a population pharmacokinetic model for adjunctive lamotrigine therapy in children

AIMS: This analysis was performed to validate a previously developed population pharmacokinetic model for lamotrigine in order to establish a basis for dosage recommendations for children. METHODS: (a) The importance of the covariates in the final model was confirmed using the model validation datas...

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Autor principal: Chen, Chao
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014392/
https://ncbi.nlm.nih.gov/pubmed/10930965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00237.x
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