Population pharmacokinetics of lamotrigine in Chinese children with epilepsy

AIM: To establish a population pharmacokinetics (PPK) model for lamotrigine (LTG) in Chinese children with epilepsy in order to formulate an individualized dosage guideline. METHODS: LTG steady-state plasma concentration data from therapeutic drug monitoring (TDM) were collected retrospectively from...

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Detalhes bibliográficos
Main Authors: He, Da-ke, Wang, Li, Qin, Jiong, Zhang, Shen, Lu, Wei, Li, Ling, Zhang, Jian-ming, Bao, Wei-qun, Song, Xiao-qing, Liu, Hai-tao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011358/
https://ncbi.nlm.nih.gov/pubmed/23103620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.118
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