Influence of cirrhosis on lamotrigine pharmacokinetics

AIMS: Lamotrigine, an antiepileptic drug, is cleared from the systemic circulation mainly by glucuronidation. The possibility of changes in the pharmacokinetics of lamotrigine in plasma owing to hepatic dysfunction has been evaluated. METHODS: Thirty-six subjects, including 24 patients with various...

Fuld beskrivelse

Na minha lista:

Bibliografiske detaljer
Main Authors:	Marcellin, P, de Bony, F, Garret, C, Altman, C, Boige, V, Castelnau, C, Laurent-Puig, P, Trinchet, J C, Rolan, P, Chen, C, Mamet, J P, Bidault, R
Format:	Artigo
Sprog:	Inglês
Udgivet:	Blackwell Science Inc 2001
Fag:	Pharmacokinetics
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2014475/ https://ncbi.nlm.nih.gov/pubmed/11421997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2001.01389.x
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!

Influence of cirrhosis on lamotrigine pharmacokinetics

Lignende værker