Genetic polymorphism of (S)-mephenytoin 4′-hydroxylation in populations of African descent

AIMS: The frequency of CYP2C19 poor metabolizers (PMs) in populations of African descent has been reported to range from 1.0% to 35.4%. In order to determine with greater certainty the frequency of CYP2C19 PMs in such black populations we have performed a meta-analysis of the studies. METHODS: Relev...

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Bibliographic Details
Main Authors: Xie, H G, Kim, R B, Stein, C M, Wilkinson, G R, Wood, A J J
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 1999
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014331/
https://ncbi.nlm.nih.gov/pubmed/10510153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00009.x
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