טוען...
Stereoselective 4′-hydroxylation of phenytoin: relationship to (S)-mephenytoin polymorphism in Japanese
Aims The aim of this study was to clarify whether phenytoin (PHT) stereoselective hydroxylation cosegregates with (S)-mephenytoin phenotype. Methods A single dose of PHT (100 mg) was administered orally to six healthy Japanese subjects in whom the genotype and phenotype of CYP2C19 had been determine...
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| Main Authors: | , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Blackwell Science Inc
1997
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042765/ https://ncbi.nlm.nih.gov/pubmed/9146858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.00572.x |
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