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BML-241 fails to display selective antagonism at the sphingosine-1-phosphate receptor, S1P(3)
BACKGROUND AND PURPOSE: The thiazolidine carboxylic acid, BML-241, has been proposed as a lead compound in development of selective antagonists at the sphingosine-1-phosphate receptor (S1P(3)), based on its inhibition of the rise in intracellular calcium concentrations ([Ca(2+)](i)) in HeLa cells ov...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014271/ https://ncbi.nlm.nih.gov/pubmed/16940990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706872 |
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