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Cardiovascular effects of sphingosine-1-phosphate and other sphingomyelin metabolites

1. Upon various stimuli, cells metabolize sphingomyelin from the cellular plasma membrane to form sphingosylphosphorylcholine (SPC) or ceramide. The latter can be further metabolized to sphingosine and then sphingosine-1-phosphate (S1P). Apart from local formation, S1P and SPC are major constituents...

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Autores principales: Alewijnse, Astrid E, Peters, Stephan L M, Michel, Martin C
Formato: Artigo
Lenguaje:Inglês
Publicado: 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575924/
https://ncbi.nlm.nih.gov/pubmed/15504747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705934
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