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Pharmacokinetics and pharmacodynamics of Ro 44–3888 after single ascending oral doses of sibrafiban, an oral platelet aggregation inhibitor, in healthy male volunteers

AIMS: This study constituted the first administration of the oral platelet inhibitor, sibrafiban, to humans. The aim was to investigate the pharmacokinetics and pharmacodynamics of Ro 44–3888, the active principle of sibrafiban, after single ascending oral doses of sibrafiban. Particular emphasis wa...

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Библиографические подробности
Главные авторы: Wittke, Bärbel, Mackie, Ian J, Machin, Samuel J, Timm, Uwe, Zell, Manfred, Goggin, Timothy
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 1999
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014180/
https://ncbi.nlm.nih.gov/pubmed/10336576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00931.x
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