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Pharmacokinetics and pharmacodynamics of Ro 44–3888 after single ascending oral doses of sibrafiban, an oral platelet aggregation inhibitor, in healthy male volunteers

AIMS: This study constituted the first administration of the oral platelet inhibitor, sibrafiban, to humans. The aim was to investigate the pharmacokinetics and pharmacodynamics of Ro 44–3888, the active principle of sibrafiban, after single ascending oral doses of sibrafiban. Particular emphasis wa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wittke, Bärbel, Mackie, Ian J, Machin, Samuel J, Timm, Uwe, Zell, Manfred, Goggin, Timothy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014180/
https://ncbi.nlm.nih.gov/pubmed/10336576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00931.x
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