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Pharmacokinetics and pharmacodynamics of Ro 44–3888 after single ascending oral doses of sibrafiban, an oral platelet aggregation inhibitor, in healthy male volunteers

AIMS: This study constituted the first administration of the oral platelet inhibitor, sibrafiban, to humans. The aim was to investigate the pharmacokinetics and pharmacodynamics of Ro 44–3888, the active principle of sibrafiban, after single ascending oral doses of sibrafiban. Particular emphasis wa...

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Detaylı Bibliyografya
Asıl Yazarlar: Wittke, Bärbel, Mackie, Ian J, Machin, Samuel J, Timm, Uwe, Zell, Manfred, Goggin, Timothy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 1999
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014180/
https://ncbi.nlm.nih.gov/pubmed/10336576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00931.x
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