Surface phospholipids in gastric injury and protection when a selective cyclooxygenase-2 inhibitor (Coxib) is used in combination with aspirin

BACKGROUND AND PURPOSE: Clinical studies demonstrate that aspirin consumption reverses the gastrointestinal (GI) benefits of coxibs, by an undefined mechanism. EXPERIMENTAL APPROACH: Rodent models were employed to investigate the effects of combinations of celecoxib and aspirin on gastric ulcerogene...

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Bibliographic Details
Main Authors: Lichtenberger, L M, Romero, J J, Dial, E J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2007
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013889/
https://ncbi.nlm.nih.gov/pubmed/17325651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707176
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