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A comparison of the pharmacological properties of guinea-pig and human recombinant 5-HT(4) receptors
BACKGROUND AND PURPOSE: 5-HT(4) receptor agonists are used therapeutically to treat disorders of reduced gastrointestinal motility. Since such compounds are evaluated in guinea-pigs, we cloned, expressed and pharmacologically characterized the guinea-pig 5-HT(4) and human 5-HT(4(b)) splice variant,...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2013860/ https://ncbi.nlm.nih.gov/pubmed/17293885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707154 |
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