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Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes

The E2A-HLF (hepatic leukemia factor) oncoprotein, generated in pro-B lymphocytes by fusion of the trans-activation domain of E2A to the basic region/leucine zipper (bZIP) domain of HLF, functions as an anti-apoptotic transcription factor in leukemic cell transformation. When introduced into interle...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ikushima, Satoshi, Inukai, Takeshi, Inaba, Toshiya, Nimer, Stephen D., Cleveland, John L., Look, A. Thomas
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122243/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2609
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