Downregulation of Bim, a Proapoptotic Relative of Bcl-2, Is a Pivotal Step in Cytokine-Initiated Survival Signaling in Murine Hematopoietic Progenitors

Two distinct signaling pathways regulate the survival of interleukin-3 (IL-3)-dependent hematopoietic progenitors. One originates from the membrane-proximal portion of the cytoplasmic domain of the IL-3 receptor (βc chain), which is shared by IL-3 and granulocyte-macrophage colony-stimulating factor...

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Detalhes bibliográficos
Main Authors: Shinjyo, Tetsuharu, Kuribara, Ryoko, Inukai, Takeshi, Hosoi, Hajime, Kinoshita, Taisei, Miyajima, Atsushi, Houghton, Peter J., Look, A. Thomas, Ozawa, Keiya, Inaba, Toshiya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86676/
https://ncbi.nlm.nih.gov/pubmed/11154272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.3.854-864.2001
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