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Engineering and production of streptokinase in a Bacillus subtilis expression-secretion system.

Streptokinase is one of the major blood-clot-dissolving agents used in many medical treatments. With the cloned streptokinase gene (skc) available, production of the secreted streptokinase from various Bacillus subtilis strains was studied. The use of the six-extracellular-protease-deficient strain,...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Principais autores: Wong, S L, Ye, R, Nathoo, S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201342/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8135514/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.60.2.517-523.1994
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