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Engineering and production of streptokinase in a Bacillus subtilis expression-secretion system.

Streptokinase is one of the major blood-clot-dissolving agents used in many medical treatments. With the cloned streptokinase gene (skc) available, production of the secreted streptokinase from various Bacillus subtilis strains was studied. The use of the six-extracellular-protease-deficient strain,...

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Detalles Bibliográficos
Publicado en:Appl Environ Microbiol
Autores principales: Wong, S L, Ye, R, Nathoo, S
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1994
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201342/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8135514/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.60.2.517-523.1994
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