Engineering and production of streptokinase in a Bacillus subtilis expression-secretion system.
Streptokinase is one of the major blood-clot-dissolving agents used in many medical treatments. With the cloned streptokinase gene (skc) available, production of the secreted streptokinase from various Bacillus subtilis strains was studied. The use of the six-extracellular-protease-deficient strain,...
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| Publié dans: | Appl Environ Microbiol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
1994
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201342/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8135514/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.60.2.517-523.1994 |
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