Insertion of the adenoviral E3 region into a recombinant viral vector prevents antiviral humoral and cellular immune responses and permits long-term gene expression

Recombinant adenoviruses (Ads) are highly efficient at transferring foreign genes to the liver in vivo; however, the duration of gene expression is limited by the host antiviral immune response, which prevents expression upon readministration of the virus. To test whether overexpression of the immun...

Descripció completa

Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Ilan, Yaron, Droguett, Gustavo, Chowdhury, Namita Roy, Li, Yongan, Sengupta, Krishna, Thummala, Narsing R., Davidson, Anne, Chowdhury, Jayanta Roy, Horwitz, Marshall S.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1997
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20132/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122239/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2587
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!