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Interactions between NO, CO and an endothelium-derived hyperpolarizing factor (EDHF) in maintaining patency of the ductus arteriosus in the mouse

BACKGROUND AND PURPOSE: Prenatal patency of ductus arteriosus is maintained by prostaglandin (PG) E(2), possibly along with nitric oxide (NO) and carbon monoxide (CO), and cyclooxygenase (COX) deletion upregulates NO. Here, we have examined enzyme source and action of NO for ductus patency and wheth...

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Autors principals: Baragatti, B, Brizzi, F, Barogi, S, Laubach, V E, Sodini, D, Shesely, E G, Regan, R F, Coceani, F
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2012984/
https://ncbi.nlm.nih.gov/pubmed/17351656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707211
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