Cyclooxygenase-1 and cyclooxygenase-2 in the mouse ductus arteriosus: individual activity and functional coupling with nitric oxide synthase

1. Prenatal patency of the ductus arteriosus is maintained by prostaglandin (PG) E(2), conceivably in concert with nitric oxide (NO). Local PGE(2) formation is sustained by cyclooxygenase-1 (COX1) and cyclooxygenase-2 (COX2), a possible exception being the mouse in which COX1, or both COXs, are repo...

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Detalhes bibliográficos
Main Authors: Baragatti, B, Brizzi, F, Ackerley, C, Barogi, S, Ballou, L R, Coceani, F
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573985/
https://ncbi.nlm.nih.gov/pubmed/12922938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705391
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