Cyclooxygenase-1 and cyclooxygenase-2 in the mouse ductus arteriosus: individual activity and functional coupling with nitric oxide synthase

1. Prenatal patency of the ductus arteriosus is maintained by prostaglandin (PG) E(2), conceivably in concert with nitric oxide (NO). Local PGE(2) formation is sustained by cyclooxygenase-1 (COX1) and cyclooxygenase-2 (COX2), a possible exception being the mouse in which COX1, or both COXs, are repo...

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Autors principals: Baragatti, B, Brizzi, F, Ackerley, C, Barogi, S, Ballou, L R, Coceani, F
Format: Artigo
Idioma:Inglês
Publicat: 2003
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Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573985/
https://ncbi.nlm.nih.gov/pubmed/12922938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705391
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