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Function of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the ductus arteriosus from foetal lamb: differential development and change by oxygen and endotoxin

1. Prenatal patency of the ductus arteriosus is maintained mainly by prostaglandin(PG) E(2). Here we have examined the relative importance of cyclo-oxygenase-1 (COX1) and cyclo-oxygenase-2 (COX2) for PGE(2) formation in the foetal lamb ductus (0.65 gestation onwards). 2. Using fluorescence microscop...

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Autors principals: Coceani, F, Ackerley, C, Seidlitz, E, Kelsey, L
Format: Artigo
Idioma:Inglês
Publicat: 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572537/
https://ncbi.nlm.nih.gov/pubmed/11156583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703779
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