EDHF function in the ductus arteriosus: evidence against involvement of epoxyeicosatrienoic acids and 12S-hydroxyeicosatetraenoic acid

We have previously shown (Ref. 2) that endothelium-derived hyperpolarizing factor (EDHF) becomes functional in the fetal ductus arteriosus on removal of nitric oxide and carbon monoxide. From this, it was proposed that EDHF originates from a cytochrome P-450 (CYP450)-catalyzed reaction being inhibit...

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Main Authors: Baragatti, Barbara, Schwartzman, Michal Laniado, Angeloni, Debora, Scebba, Francesca, Ciofini, Enrica, Sodini, Daria, Ottaviano, Virginia, Nencioni, Simona, Paolicchi, Aldo, Graves, Joan P., Zeldin, Darryl C., Gotlinger, Katherine, Luin, Stefano, Coceani, Flavio
Format: Artigo
Language:Inglês
Published: American Physiological Society 2009
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793138/
https://ncbi.nlm.nih.gov/pubmed/19801493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00576.2009
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