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Mechanisms of G protein activation via the D(2) dopamine receptor: evidence for persistent receptor/G protein interaction after agonist stimulation

BACKGROUND AND PURPOSE: The aim of this report is to study mechanisms of G protein activation by agonists. EXPERIMENTAL APPROACH: The association and dissociation of guanosine 5′-O-(3-[(35)S]thio)triphosphate ([(35)S]GTPγS) binding at G proteins in membranes of CHO cells stably transfected with the...

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Bibliografiske detaljer
Main Authors: Quirk, K, Roberts, D J, Strange, P G
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2012977/
https://ncbi.nlm.nih.gov/pubmed/17351658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707197
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