Inhibition of Aminoglycoside 6′-N-Acetyltransferase Type Ib-Mediated Amikacin Resistance by Antisense Oligodeoxynucleotides

Amikacin has been very useful in the treatment of infections caused by multiresistant bacteria because it is refractory to the actions of most modifying enzymes. However, the spread of AAC(6′)-I-type acetyltransferases, enzymes capable of catalyzing inactivation of amikacin, has rendered this antibi...

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הוצא לאור ב:	Antimicrob Agents Chemother
Principais autores:	Sarno, Renee, Ha, Hongphuc, Weinsetel, Natalia, Tolmasky, Marcelo E.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2003
נושאים:	Mechanisms of Resistance
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201158/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14506044/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.10.3296-3304.2003
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