Antimony Uptake Systems in the Protozoan Parasite Leishmania and Accumulation Differences in Antimony-Resistant Parasites

The first line drug against leishmaniasis consists of pentavalent antimony [Sb(V)], but there is general belief that the active form of the metal is the trivalent form [Sb(III)]. In this study, we have quantified the accumulation of Sb(V) and Sb(III) in Leishmania by using inductively coupled plasma...

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Bibliographic Details
Main Authors: Brochu, Christian, Wang, Jingyu, Roy, Gaétan, Messier, Nadine, Wang, Xiao-Yan, Saravia, Nancy G., Ouellette, Marc
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC201146/
https://ncbi.nlm.nih.gov/pubmed/14506011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.10.3073-3079.2003
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