Selective cytotoxicity against human tumour cells by a vindesine-monoclonal antibody conjugate.

The anti-mitotic drug vindesine was coupled chemically to a monoclonal antibody raised originally against the human osteogenic sarcoma cell line, 791T. The cytotoxicity of the conjugate in vitro was tested, in comparison with free vindesine, against sarcoma 791T and other antigenically cross-reactiv...

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Bibliographic Details
Main Authors: Embleton, M. J., Rowland, G. F., Simmonds, R. G., Jacobs, E., Marsden, C. H., Baldwin, R. W.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1983
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2011258/
https://ncbi.nlm.nih.gov/pubmed/6571783
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