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Selective cytotoxicity against human tumour cells by a vindesine-monoclonal antibody conjugate.

The anti-mitotic drug vindesine was coupled chemically to a monoclonal antibody raised originally against the human osteogenic sarcoma cell line, 791T. The cytotoxicity of the conjugate in vitro was tested, in comparison with free vindesine, against sarcoma 791T and other antigenically cross-reactiv...

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Bibliografiske detaljer
Main Authors: Embleton, M. J., Rowland, G. F., Simmonds, R. G., Jacobs, E., Marsden, C. H., Baldwin, R. W.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1983
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2011258/
https://ncbi.nlm.nih.gov/pubmed/6571783
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