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Antigenicity and drug susceptibility of human osteogenic sarcoma cells "escaping" a cytotoxic methotrexate-albumin-monoclonal antibody conjugate.

Cells of osteogenic sarcoma line 791T were treated in vitro with a selectively cytotoxic methotrexate-human serum albumin-monoclonal antibody conjugate at concentrations which were toxic but allowed the "escape" of a small number of tumour cell colonies (less than 0.3% compared with contro...

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Autori principali: Embleton, M. J., Garnett, M. C., Jacobs, E., Baldwin, R. W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1984
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976728/
https://ncbi.nlm.nih.gov/pubmed/6586198
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