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Interleukin-18 Facilitates the Early Antimicrobial Host Response to Escherichia coli Peritonitis

To determine the role of endogenous interleukin-18 (IL-18) during peritonitis, IL-18 gene-deficient (IL-18 KO) mice and wild-type mice were intraperitoneally (i.p.) infected with Escherichia coli, the most common causative agent found in septic peritonitis. Peritonitis was associated with a bacteria...

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Published in:Infect Immun
Main Authors: Weijer, Sebastiaan, Sewnath, Miguel E., de Vos, Alex F., Florquin, Sandrine, Sluis, Koen van der, Gouma, Dirk J., Takeda, Kiyoshi, Akira, Shizuo, Poll, Tom van der
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2003
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201063/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14500466/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.10.5488-5497.2003
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