Experimental Mycobacterium tuberculosis Infection of Cynomolgus Macaques Closely Resembles the Various Manifestations of Human M. tuberculosis Infection

Nonhuman primates were used to develop an animal model that closely mimics human Mycobacterium tuberculosis infection. Cynomolgus macaques were infected with low doses of virulent M. tuberculosis via bronchoscopic instillation into the lung. All monkeys were successfully infected, based on tuberculi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Capuano, Saverio V., Croix, Denise A., Pawar, Santosh, Zinovik, Angelica, Myers, Amy, Lin, Philana L., Bissel, Stephanie, Fuhrman, Carl, Klein, Edwin, Flynn, JoAnne L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2003
Pynciau:
Bacterial Infections
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC201048/
https://ncbi.nlm.nih.gov/pubmed/14500505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.10.5831-5844.2003
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