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Glomerulosclerosis is transmitted by bone marrow–derived mesangial cell progenitors

We found that ROP Os/+ (Os/+) mice had diffuse glomerulosclerosis and glomerular hypertrophy and that their mesangial cells (the vascular smooth muscle cells of the glomerulus) displayed an apparent sclerosing phenotype. Since mesangial cells are the major source of scar tissue in glomerulosclerosis...

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Main Authors: Cornacchia, Flavia, Fornoni, Alessia, Plati, Anna Rita, Thomas, Alton, Wang, Yingcai, Inverardi, Luca, Striker, Liliane J., Striker, Gary E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC200982/
https://ncbi.nlm.nih.gov/pubmed/11733560
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