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Glomerulosclerosis is transmitted by bone marrow–derived mesangial cell progenitors

We found that ROP Os/+ (Os/+) mice had diffuse glomerulosclerosis and glomerular hypertrophy and that their mesangial cells (the vascular smooth muscle cells of the glomerulus) displayed an apparent sclerosing phenotype. Since mesangial cells are the major source of scar tissue in glomerulosclerosis...

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Pubblicato in:J Clin Invest
Autori principali: Cornacchia, Flavia, Fornoni, Alessia, Plati, Anna Rita, Thomas, Alton, Wang, Yingcai, Inverardi, Luca, Striker, Liliane J., Striker, Gary E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2001
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Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC200982/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11733560/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI12916
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