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Glomerulosclerosis is transmitted by bone marrow–derived mesangial cell progenitors

We found that ROP Os/+ (Os/+) mice had diffuse glomerulosclerosis and glomerular hypertrophy and that their mesangial cells (the vascular smooth muscle cells of the glomerulus) displayed an apparent sclerosing phenotype. Since mesangial cells are the major source of scar tissue in glomerulosclerosis...

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Bibliografski detalji
Glavni autori: Cornacchia, Flavia, Fornoni, Alessia, Plati, Anna Rita, Thomas, Alton, Wang, Yingcai, Inverardi, Luca, Striker, Liliane J., Striker, Gary E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2001
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC200982/
https://ncbi.nlm.nih.gov/pubmed/11733560
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