Expression of a dominant-negative type II transforming growth factor β (TGF-β) receptor in the epidermis of transgenic mice blocks TGF-β-mediated growth inhibition

To determine whether a functional type II receptor of transforming growth factor β (TGF-β) is required to mediate the growth inhibitory effect of TGF-β on the skin in vivo, we have generated transgenic mice that overexpress a dominant negative-type II TGF-β receptor (ΔβRII) in the epidermis. The ΔβR...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wang, Xiao-Jing, Greenhalgh, David A., Bickenbach, Jackie R., Jiang, Aibo, Bundman, Donnie S., Krieg, Thomas, Derynck, Rik, Roop, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20097/
https://ncbi.nlm.nih.gov/pubmed/9122204
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados