Supercoil-induced extrusion of a regulatory DNA hairpin

Bacteriophage N4 virion RNA polymerase (N4 vRNAP) promoters contain inverted repeats, which form a 5- to 7-base-pair stem, 3-base loop hairpin that is required for vRNAP recognition. We show that, contrary to certain theoretical predictions, hairpin extrusion can occur at physiological superhelical...

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Hauptverfasser: Dai, Xing, Greizerstein, Miriam B., Nadas-Chinni, Krisztina, Rothman-Denes, Lucia B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences of the USA 1997
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC20060/
https://ncbi.nlm.nih.gov/pubmed/9122167
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