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Supercoil-induced extrusion of a regulatory DNA hairpin

Bacteriophage N4 virion RNA polymerase (N4 vRNAP) promoters contain inverted repeats, which form a 5- to 7-base-pair stem, 3-base loop hairpin that is required for vRNAP recognition. We show that, contrary to certain theoretical predictions, hairpin extrusion can occur at physiological superhelical...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Dai, Xing, Greizerstein, Miriam B., Nadas-Chinni, Krisztina, Rothman-Denes, Lucia B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20060/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122167/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2174
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