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Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses

On the basis of results of studies using high doses of estrogens, exposure to estrogen during fetal life is known to inhibit prostate development. However, it is recognized in endocrinology that low concentrations of a hormone can stimulate a tissue, while high concentrations can have the opposite e...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Saal, Frederick S. vom, Timms, Barry G., Montano, Monica M., Palanza, Paola, Thayer, Kristina A., Nagel, Susan C., Dhar, Minati D., Ganjam, V. K., Parmigiani, Stefano, Welshons, Wade V.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1997
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20042/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9050904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.5.2056
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