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Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses

On the basis of results of studies using high doses of estrogens, exposure to estrogen during fetal life is known to inhibit prostate development. However, it is recognized in endocrinology that low concentrations of a hormone can stimulate a tissue, while high concentrations can have the opposite e...

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Detalhes bibliográficos
Main Authors: Saal, Frederick S. vom, Timms, Barry G., Montano, Monica M., Palanza, Paola, Thayer, Kristina A., Nagel, Susan C., Dhar, Minati D., Ganjam, V. K., Parmigiani, Stefano, Welshons, Wade V.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20042/
https://ncbi.nlm.nih.gov/pubmed/9050904
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