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Severe inflammatory arthritis and lymphadenopathy in the absence of TNF
It has been postulated that TNF has a pivotal role in a cytokine cascade that results in joint inflammation and destruction in rheumatoid arthritis (RA). To evaluate this, we examined the response of TNF-deficient (Tnf(–/–)) mice in two models of RA. Collagen-induced arthritis (CIA) was induced by i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC200197/ https://ncbi.nlm.nih.gov/pubmed/11413159 |
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