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Activation of sickle red blood cell adhesion via integrin-associated protein/CD47–induced signal transduction

Peripheral human red blood cells (RBCs) are not generally known to become activated and adhesive in response to cell signaling. We show, however, that soluble thrombospondin via integrin-associated protein (IAP; CD47) increases the adhesiveness of sickle RBCs (SS RBCs) by activating signal transduct...

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Bibliographische Detailangaben
Hauptverfasser: Brittain, Julia E., Mlinar, Kathryn J., Anderson, Christopher S., Orringer, Eugene P., Parise, Leslie V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC200189/
https://ncbi.nlm.nih.gov/pubmed/11413163
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