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Costimulation of T Cell Activation by Integrin-associated Protein (CD47) Is an Adhesion-dependent, CD28-independent Signaling Pathway

The integrin-associated protein (IAP, CD47) is a 50-kD plasma membrane protein with a single extracellular immunoglobulin variable (IgV)-like domain, a multiply membrane-spanning segment, and alternatively spliced short cytoplasmic tails. On neutrophils, IAP has been shown to function in a signaling...

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Auteurs principaux: Reinhold, Martina I., Lindberg, Frederik P., Kersh, Gilbert J., Allen, Paul M., Brown, Eric J.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211576/
https://ncbi.nlm.nih.gov/pubmed/8996237
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