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Activation of sickle red blood cell adhesion via integrin-associated protein/CD47–induced signal transduction

Peripheral human red blood cells (RBCs) are not generally known to become activated and adhesive in response to cell signaling. We show, however, that soluble thrombospondin via integrin-associated protein (IAP; CD47) increases the adhesiveness of sickle RBCs (SS RBCs) by activating signal transduct...

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Detalhes bibliográficos
Main Authors: Brittain, Julia E., Mlinar, Kathryn J., Anderson, Christopher S., Orringer, Eugene P., Parise, Leslie V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC200189/
https://ncbi.nlm.nih.gov/pubmed/11413163
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