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Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome

N-acetyl-l-leucyl-l-leucyl-l-norleucinal (LLnL), which reversibly inhibits the proteasome in addition to other proteases, and a more specific irreversible inhibitor of the proteasome, lactacystin, were found to cause the accumulation of major histocompatibility complex (MHC) class I heavy chains in...

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Bibliografiset tiedot
Päätekijät: Hughes, Eric A., Hammond, Craig, Cresswell, Peter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences of the USA 1997
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC20014/
https://ncbi.nlm.nih.gov/pubmed/9050876
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