Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome
N-acetyl-l-leucyl-l-leucyl-l-norleucinal (LLnL), which reversibly inhibits the proteasome in addition to other proteases, and a more specific irreversible inhibitor of the proteasome, lactacystin, were found to cause the accumulation of major histocompatibility complex (MHC) class I heavy chains in...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20014/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9050876/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.5.1896 |
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